CHIRAL HEPTYNE DERIVATIVES FOR THE PREPARATION OF EPOTHILONES AND PROCESSES FOR THEIR PREPARATION
摘要
The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds. The intermediates used are represented by formulae II and III, wherein R is selected from H, alkyl and substituded alkyl and X1 is an oxygen protecting group.
申请公布号
WO2005101950(A1)
申请公布日期
2005.11.03
申请号
WO2005EP04492
申请日期
2005.04.21
申请人
SCHERING AKTIENGESELLSCHAFT;PLATZEK, JOHANNES;PETROV, ORLIN;WILLUHN, MARC;GRASKE, KLAUS-DIETER;SKUBALLA, WERNER
发明人
PLATZEK, JOHANNES;PETROV, ORLIN;WILLUHN, MARC;GRASKE, KLAUS-DIETER;SKUBALLA, WERNER