发明名称 |
USE OF C-KIT INHIBITORS FOR TREATING INFLAMMATORY MUSCLE DISORDERS INCLUDING MYOSITIS AND MUSCULAR DYSTROPHY |
摘要 |
The present invention relates to a method for treating inflammatory muscle disorders including myositis and muscular dystrophy comprising administering a compound capable of depleting mast cells or a compound inhibiting mast cell degranulation, to a human in need of such treatment. Such compounds can be chosen from c-kit inhibitors and more particularly non-toxic, selective and potent c-kit inhibitors. Preferably, said inhibitor is unable to promote dea th of IL-3 dependent cells cultured in presence of IL-3.
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申请公布号 |
CA2564568(A1) |
申请公布日期 |
2005.11.03 |
申请号 |
CA20052564568 |
申请日期 |
2005.04.19 |
申请人 |
AB SCIENCE |
发明人 |
KINET, JEAN-PIERRE;MOUSSY, ALAIN |
分类号 |
A61K31/426;A61K31/421;A61K31/506;A61P21/00 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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