发明名称 |
Method and equipment for fiber optic high-resolution, in particular confocal, fluorescence imaging |
摘要 |
A method using an image guide having several thousands of optical fibers, an excitation signal emitted by a source, deflected and injected by turns into the optical fibers, each excitation point of the tissue in the fiber output emitting in return a fluorescence signal collected by the fiber, then detected and digitized to form an image element. The method provides for the focussing of the beam in the fiber output to excite a subsurface plane to produce a confocal image, and the production of a divergent beam in the fiber output capable of exciting a micro-volume of the tissue from the surface. The method consists in deflecting the excitation signal at a speed corresponding to acquisition of a number of images per second sufficient for real time use and in detecting the fluorescence signal at a detecting frequency corresponding to a minimum frequency for sampling the fibers one by one.
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申请公布号 |
US2005242298(A1) |
申请公布日期 |
2005.11.03 |
申请号 |
US20050521607 |
申请日期 |
2005.01.18 |
申请人 |
MAUNA KEA TECHNOLOGIES |
发明人 |
GENET MAGALIE;VIELLEROBE BERTRAND;BERIER FREDERIC;CLADE SOPHIE |
分类号 |
G01N21/64;A61B1/00;A61B1/04;A61B5/00;G02B21/00;G02B23/24;G02B23/26;G02B26/10;H04N1/028;(IPC1-7):G01N21/64 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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