发明名称 |
Secondary amino anilinic piperidines as mch1 antagonists and uses thereof |
摘要 |
This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compounds of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.
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申请公布号 |
US2005245743(A1) |
申请公布日期 |
2005.11.03 |
申请号 |
US20040518675 |
申请日期 |
2004.12.17 |
申请人 |
MARZABADI MOHAMMAD R;YU JIANG;LU KAI;CHEN CHIEN-AN;DE LEON JOHN E;WETZEL JOHN |
发明人 |
MARZABADI MOHAMMAD R.;YU JIANG;LU KAI;CHEN CHIEN-AN;DE LEON JOHN E.;WETZEL JOHN |
分类号 |
A61K31/44;A61K31/451;A61K31/4545;A61K31/506;A61P3/04;A61P13/02;A61P25/22;A61P25/24;A61P43/00;C07D211/26;C07D211/70;C07D401/12;(IPC1-7):C07D211/68;C07D43/02;C07D41/02 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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