Methods and systems for identifying genes, splice variants, and transcripts using an evidence mapping approach

摘要

The present teachings contain a method and system for gene and splice variant identification and display. The teachings employ evidence from various genomic and proteomic databases. The method can be run on a computer system and performs its function by mapping evidence to a genome under study and then collapsing overlapping evidence to form clusters. Various rules are taught that can be used to identify unique transcripts and gene boundaries. Clusters can be displayed visually or in report format. Regardless of format, the evidence leading the cluster definitions can be seen.