BONE DELIVERY CONJUGATES AND METHOD OF USING SAME TO TARGET PROTEINS TO BONE
摘要
A bone delivery conjugate having a structure selected from the group consisting of :A) X-Dn-Y-protein-Z; and B) Z-protein-Y- Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and Dn is a poly aspartate wherein n = 10 to 16. Compositions comprising same and uses thereof.
申请公布号
WO2005103263(A1)
申请公布日期
2005.11.03
申请号
WO2005CA00615
申请日期
2005.04.21
申请人
ENOBIA PHARMA INC.;CRINE, PHILIPPE;BOILEAU, GUY;LEMIRE, ISABELLE;LOISEL, THOMAS, P.
发明人
CRINE, PHILIPPE;BOILEAU, GUY;LEMIRE, ISABELLE;LOISEL, THOMAS, P.