NOVEL COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND METHODS FOR IDENTIFYING SAME

摘要

The present invention relates to methods of identifying compounds that influence the amyloid-beta precursor protein processing in a cell, and/or that influence the activity or levels of proteins involved in the processing of the amyloid beta precursor protein. It furthermore relates to the compounds that may be identified using the methods of the invention and to use of said compounds in the treatment of neurological disorders such as Alzheimer's disease. More specifically, it relates to compounds that target the AVPR1a, AVPR1b and/or AVPR2 receptors.