FORMYLPEPTIDE RECEPTOR (FPR) AS A TARGET FOR ANTI-MALIGNANT GLIOMA THERAPY
摘要
<p>The present invention relates, e.g., to a method for inhibiting a formylpeptide receptor (FPR)-mediated activity of a glioma cell expressing FPR, comprising contacting the cell with an effective amount of an agent that inhibits expression and/or activity of the FPR. The cell can be in vitro or in vivo. Also disclosed are inhibitory agents and pharmaceutical compositions for carrying out this method; diagnostic methods for identifying highly malignant glioma cells; and a method for identifying an agent that inhibits an FPR-mediated activity of a glioma cell.</p>
申请公布号
WO2005103255(A1)
申请公布日期
2005.11.03
申请号
WO2005US05652
申请日期
2005.02.22
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;WANG, JI, MING;ZHOU, YE;LE, YING-YING;GONG, WANGHUA
发明人
WANG, JI, MING;ZHOU, YE;LE, YING-YING;GONG, WANGHUA
