| 发明名称 |
DIHYDRO-BENZO[b][1,4]DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II |
| 摘要 |
This invention is a dihydro-benzo[b][1,4]diazepin-2-one derivative of the formulawherein R1, R2, R3, X and Y are as defined in the specification. The invention includes pharmaceutical compositions containing these compounds, a process for their preparation, their use in preparation of pharmaceutical compositions and administration of an effective amount of the compounds for the treatment or prevention of acute and/or chronic neurological disorders to a patient in need of such treatment. |
| 申请公布号 |
HRP20030792(A2) |
申请公布日期 |
2005.10.31 |
| 申请号 |
HR2003P000792 |
申请日期 |
2003.10.01 |
| 申请人 |
F. HOFFMANN - LA ROCHE AG |
发明人 |
GEO ADAM;ERWIN GOETSCHI;VINCENT MUTEL;JUERGEN WICHMANN;THOMAS JOHANNES WOLTERING |
| 分类号 |
C07D243/12;A61K31/551;A61K31/5513;A61P25/00;A61P25/18;A61P25/28;A61P43/00;C07D401/04;C07D403/04;C07D403/10;C07D403/14;C07D413/10;C07D413/14;C07D417/10;C07D417/14 |
主分类号 |
C07D243/12 |
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