| 发明名称 |
METHOD FOR THE PREPARATION of 4'-TRIFLUOROMETHYLBIPHENYL-2-CARBOXAMIDO-(1,2,3,4-TETRAHYDROISOQUINOLINE-6-YL) AND ITS SALTS |
| 摘要 |
The invention is directed to process for the preparation of 4'-trifluoromethylbiphenyl-2-carboxamido-(1,2,3,4-tetrahydroisoquinoline-6-yl) and its acid adjunctive salts. The said compounds are used as intermediate products in the synthesizing of amides inhibiting Apo B-secretion/MTP, i.e. inhibitors of the microsome transfer of triglyceride proteins (MTP) and/or apolypoproteins B (Apo B) secretion.
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| 申请公布号 |
BG108830(A) |
申请公布日期 |
2005.10.31 |
| 申请号 |
BG19990108830 |
申请日期 |
1999.05.26 |
| 申请人 |
PFIZER INC. |
发明人 |
CHANG GEORGE;QUALLICH GEORGE |
| 分类号 |
C07D217/22;A61K31/47;A61K31/472;A61K31/4725;A61K31/496;A61K31/5377;A61P3/04;A61P3/06;A61P3/10;A61P43/00;C07D217/04;C07D401/04;C07D401/06;C07D405/04;C07D405/06;C07D409/06;C07D417/06;(IPC1-7):C07D217/04 |
主分类号 |
C07D217/22 |
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