Rabbit hemorrhagic disease virus (RHDV) recombinant capsids and proteins, diagnostic kits and vaccines containing them

摘要

Recombinant capsids and recombinant proteins of rabbit hemorrhagic disease virus (RHDV) have been produced, in a recombinant baculovirus expression system replicated on an insect cell culture. These recombinant capsids and proteins are immunogenically and antigenically analogous to the RHDV native VP60 protein, and are suitable for the formulation of vaccines capable of efficaciously protecting rabbits against RHDV, as well as for the preparation of diagnostic kits suitable for the detection of both the presence of antibodies that recognize RHDV and the presence of RHDV in a biological sample from rabbit. This invention is of interest to Veterinary Medicine.