发明名称 |
Method of treating cancer wherein the cancer expresses epidermal growth factor receptor comprising administration of humanized anti-ErbB2 antibodies |
摘要 |
<p>Described is an article of manufacture comprising a container and a composition contained therein, wherein the composition comprises an antibody which binds ErbB2 and blocks binding of monoclonal antibody 2C4 to ErbB2, and further comprising a package insert indicating that the composition can be used to treat cancer which expresses epidermal growth factor receptor (EGFR). Also described is the use of antibody which binds ErbB2 and blocks binding of monoclonal antibody 2C4 to ErbB2 in the manufacture of a medicament for treating cancer, wherein the cancer expresses epidermal growth factor receptor (EGFR). The antibody blocks ligand activation of an ErbE receptor. (62) Divided out of 516830</p> |
申请公布号 |
NZ531426(A) |
申请公布日期 |
2005.10.28 |
申请号 |
NZ20000531426 |
申请日期 |
2000.06.23 |
申请人 |
GENENTECH, INC |
发明人 |
ADAMS, CAMELLIA W;PRESTA, LEONARD G;SLIWKOWSKY, MARK |
分类号 |
A61K45/00;A61K31/337;A61K31/429;A61K31/437;A61K31/4985;A61K31/513;A61K31/555;A61K33/24;A61K39/395;A61K47/48;A61P35/00;A61P43/00;C07K16/32;(IPC1-7):A61K47/48 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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