| 发明名称 |
Pyrazole compounds useful as protein kinase inhibitors |
| 摘要 |
This invention describes novel pyrazole compound of formula IIc.. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
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| 申请公布号 |
NZ526469(A) |
申请公布日期 |
2005.10.28 |
| 申请号 |
NZ20010526469 |
申请日期 |
2001.12.19 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
BEBBINGTON, DAVID;CHARRIER, JEAN-DAMIEN;DAVIES, ROBERT;EVERITT, SIMON;KAY, DAVID;KNEGTEL, RONALD;PATEL, SANJAY |
| 分类号 |
C12N9/99;A61K;A61K31/435;A61K31/4439;A61K31/444;A61K31/4709;A61K31/4725;A61K31/496;A61K31/501;A61K31/506;A61K31/513;A61K31/517;A61K31/519;A61K31/53;A61K31/5377;A61K31/541;A61K31/55;A61K45/00;A61P;A61P1/00;A61P3/08;A61P3/10;A61P3/14;A61P5/00;A61P5/18;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P11/06;A61P13/12;A61P15/00;A61P17/06;A61P17/14;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P21/02;A61P21/04;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P29/00;A61P31/12;A61P31/18;A61P31/20;A61P31/22;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D407/14;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D473/16;C07D487/04;C07D491/04;C07D493/04;C07D495/04;C07D498/04;C07D513/04;C07D521/00;(IPC1-7):C07D403/12 |
主分类号 |
C12N9/99 |
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