发明名称 Peptides as NS3-serine protease inhibitors of hepatitis C virus
摘要 Peptides of formula (I) as NS3-serine protease inhibitors of hepatitis C virus that have HCV protease inhibitory activity and methods for preparing these peptide compounds are disclosed, wherein the variables are as defined in the specification. Pharmaceutical compositions comprising these compounds that are useful for treating disorders associated with the HCV protease are also disclosed.
申请公布号 NZ523782(A) 申请公布日期 2005.10.28
申请号 NZ20010523782 申请日期 2001.07.19
申请人 DENDREON CORPORATION;SCHERING CORPORATION 发明人 CHEN, KEVIN X;VENKATRAMAN, SRIKANTH;VACCARO, HENRY A;SAKSENA, ANIL K;GIRIJAVALLABHAN, VIYYOOR MOOPIL;LOVEY, RAYMOND G;JAO, EDWIN E;BENNETT, FRANK;MCCORMICK, JINPING L;WANG, HAIYAN;PIKE, RUSSELL E;BOGEN, STEPHANE L;CHAN, TIN-YAU;LIU, YI-TSUNG;ZHU, ZHAONING;NJOROGE, F GEORGE;ARASAPPAN, ASHOK;PAREKH, TEJAL N;GANGULY, ASHIT K;PINTO, PATRICK A;SANTHANAM, BAMA;WU, WANLI;HENDRATA, SISKA;HUANG, YUHUA;KEMP, SCOTT JEFFREY;LEVY, ODILE ESTHER;LIM-WILBY, MARGUERITA;TAMURA, SUSAN Y
分类号 A61K45/00;A61K31/7056;A61K38/00;A61K38/21;A61P31/14;A61P43/00;C07K5/02;C07K5/08;C07K5/087;C07K7/02;(IPC1-7):C07K5/062;C07K5/065;A61K38/05 主分类号 A61K45/00
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