Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

摘要

Disclosed are Perfluoroalkyl-containing complexes with polar radicals of general formula (I); in which, Rf is a perfluorinated, straight-chain or branched carbon chain with the formula -CnF2nE, in which E represents a terminal fluorine, chlorine, bromine iodine or H atom, and n stands for 4-30; K stands for a metal complex of general formula (II), (III) (IV), (VA) or (VB), (VI) or (VII); G represents a radical that is functionalized in at least three places and that is selected from formulas (a) to (i), whereby alpha means the binding site of G to complex K, beta is the binding site of G to radical R and gamma represents the binding site of G to radical Z; Z stands for formula (VIII). Further disclosed are processes for the production of compounds of the general formula (I), and the use of these compounds for the production of contrast media for use in NMR and X-ray diagnosis, infarction and necrosis imaging, radiodiagnosis and radiotherapy, and other forms of medical imaging.