<p>The present invention provides a process for the preparation 6-[3-(hetero)aryloxy-2-fluoro-benzyl] -2H-pyridazin-3-one compounds of formula VIII wherein R<2> is an optionally substituted aryl or an optionally substituted heteroaryl, X is C1-6 alkyl, halogen, or a function group readily derived therefrom and R<5> is H, C02R<5a> or formula C; R<5a >is hydrogen or C1-6 alkyl; R<4c >is hydrogen or C1-6 alkyl.</p>
申请公布号
WO2005100323(A1)
申请公布日期
2005.10.27
申请号
WO2005EP03653
申请日期
2005.04.07
申请人
F. HOFFMANN-LA ROCHE AG;KERTESZ, DENIS, JOHN;MARTIN, MICHAEL;PALMER, WYLIE, SOLANG