发明名称 Respiratory syncytial virus replication inhibitors
摘要 This invention concerns the use of compounds of formula (I) wherein -a<SUP>1</SUP>=a<SUP>2</SUP>-a<SUP>3</SUP>=a<SUP>4</SUP>- is a radical of formula -CH=CH-CH=CH, -N-CH-CH-CH-, -CH-N-CH-CH-, -CH-CH-N-CH-, -CH-CH-CH-N- wherein each hydrogen atom may optionally be substituted; Q is a radical of formulas (b-1), (b-2), (b-3), (b-4), (b-5), (b-6), (b-7), (b-8). G is a direct bond or C<SUB>1-10</SUB>alkanediyl; R<SUP>1 </SUP>is an optionally substituted monocyclic heterocycle; for the manufacture of a medicament for the treatment of viral infections, in particular RSV infections. Certain compounds of formula (I) are new.
申请公布号 US2005239771(A1) 申请公布日期 2005.10.27
申请号 US20050144126 申请日期 2005.06.03
申请人 JANSSEN PHARMACEUTICA, N.V. 发明人 JANSSENS FRANS E.;MEERSMAN KATHLEEN P.M.;SOMMEN FRANCOIS M.;GUILLEMONT JEROME E.G.;LACRAMPE JEAN F.A.;ANDRIES KOENRAAD JOZEF L.M.
分类号 A61K31/4184;A61K31/4188;A61K31/443;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4745;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/55;A61K31/551;A61P31/12;A61P31/14;C07D401/06;C07D401/14;C07D405/14;C07D413/14;C07D417/14;C07D471/04;(IPC1-7):A61K31/551;A61K31/474;A61K31/418 主分类号 A61K31/4184
代理机构 代理人
主权项
地址