发明名称 |
IMMUNOKINASES |
摘要 |
A synthetic, soluble, endogenous complex formed from at least one component A and at least one component B, whereby component A comprises a binding domain for extra-cellular surface structures that internalize upon binding of component A of said complex, and component B has a constitutive catalytic kinase activity and effects cell biosynthesis/signalling including cell death after internalization. The complex allows to influence the growth and the physiology of cells. In particular said complex, nucleic acid molecules encoding it, cells transfected or transformed with these nucleic acid molecules are usable for the preparation of medicaments for the treatment of proliferative diseases, inflammatory diseases, allergies and autoimmune diseases. |
申请公布号 |
WO2005068616(A3) |
申请公布日期 |
2005.10.27 |
申请号 |
WO2005EP50131 |
申请日期 |
2005.01.13 |
申请人 |
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;BARTH, STEFAN;TUR, MEHMET KEMAL;STOECKER, MICHAEL;FISCHER, RAINER |
发明人 |
BARTH, STEFAN;TUR, MEHMET KEMAL;STOECKER, MICHAEL;FISCHER, RAINER |
分类号 |
C07K19/00;C12N9/12;C12N15/62 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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