发明名称 Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
摘要 The present invention relates to alkyne compounds of general formula I wherein the groups and radicals A, B, W, X, Y, Z, R<SUP>1 </SUP>and R<SUP>2 </SUP>have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one alkyne according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
申请公布号 US2005239826(A1) 申请公布日期 2005.10.27
申请号 US20050104915 申请日期 2005.04.13
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 STENKAMP DIRK;MUELLER STEPHAN G.;LUSTENBERGER PHILIPP;LEHMANN-LINTZ THORSTEN;ROTH GERALD J.;RUDOLF KLAUS;SCHINDLER MARCUS;THOMAS LEO;LOTZ RALF R.
分类号 A61K31/44;A61K31/4439;A61K31/4709;(IPC1-7):A61K31/470;A61K31/443;C07D45/02;C07D43/02 主分类号 A61K31/44
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