发明名称 EXPRESSION SYSTEM FOR PREPARING IL-15/FC FUSION PROTEINS ANDITS USE
摘要 The invention relates to an expression system containing one or more nucleic acid(s) comprising at least one nucleic acid for an interleukin 15/Fc (IL- 15/Fc) fusion protein, at least one promotor, at least one nucleic acid for a CD5 leader and, where appropriate, at least one nucleic acid for a selectabl e marker gene; to a nucleic acid comprising the components of the said expression system and to a host cell containing the expression system or the nucleic acid. Furthermore, the invention relates to a process for preparing an IL-15/Fc fusion protein, using the expression system, and to the use of the expression system, the nucleic acid, the host cell or the CD5 leader for expression in host cells.
申请公布号 CA2562761(A1) 申请公布日期 2005.10.27
申请号 CA20052562761 申请日期 2005.04.13
申请人 F. HOFFMANN-LA ROCHE AG 发明人 MOLL, THOMAS;ZAHN, STEFANIE;DREHER, INGEBORG;HERRMANN, ANDREAS
分类号 C07K14/54;C12N15/62 主分类号 C07K14/54
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