摘要 |
<p>A medicine for prevention and/or treatment of arteriosclerosis and diseases associated therewith, comprising as active ingredients a substance having the efficacy of retinoid X receptor (RXR) activation (for example, 4-[2,3-(2,5-dimethyl-2,5-hexano)dibenzo[b,f][1,4]thiazepin-11-yl]benzoic acid or 2-[N-cyclopropylmethyl-N-(5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalen-2-yl)amino]pyrimidine-5-carboxylic acid, etc.) and a substance having the efficacy of activating peroxisome proliferator-activated receptor gamma (PPARgamma) (for example, troglitazone or rosiglitazone, etc.).</p> |