摘要 |
PROBLEM TO BE SOLVED: To provide an automatic solid phase synthesizing apparatus not using an excess reagent from the viewpoint of resource conservation and energy saving and requiring no power means of a stirring and mixing. SOLUTION: The automatic solid phase synthesizing apparatus includes a keeping container of a plurality of reaction reagents and solvents for performing synthetic reaction, piping for supplying the reaction reagents and the solvents to a fine tubular reaction pipe, a liquid feed means for feeding the reaction reagents and the solvents to the fine tubular reaction pipe, a changeover valve for supplying only the desired reaction reagent and the solvent to the fine tubular reactor and a fine tubular reactor filled with a reactive substrate fixing carrier. After a necessary amount of the reaction reagent is fed into the fine tubular reactor, desired synthesizing reaction is performed in a state that the feed of the reaction reagent is stopped. After the completion of reaction, the reaction reagent other than the reaction product fixed to a carrier is washed off by the solvent. COPYRIGHT: (C)2006,JPO&NCIPI
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