发明名称 |
ANIMAL MODEL, CELLS, AND TREATMENT FOR MALIGNANT MELANOMA |
摘要 |
The present invention provides transgenic non-human animal models and cell lines which express a metabotropic glutamate receptor 1 in a melanocyte-specific manner and, as a result, exhibit a predisposition to the development of melanoma. The invention further teaches methods of using the transgenic animals and cell lines to identify therapeutic agents. Diagnostic methods for detecting a melanoma are also provided. |
申请公布号 |
WO2005099449(A2) |
申请公布日期 |
2005.10.27 |
申请号 |
WO2005US10453 |
申请日期 |
2005.03.28 |
申请人 |
RUTGERS, THE STATE UNIVERSITY;CHEN, SUZIE |
发明人 |
CHEN, SUZIE |
分类号 |
A01K67/027;C07K14/705;C12N5/09;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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