| 发明名称 |
PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY |
| 摘要 |
The present invention relates to compounds of the formula (1) and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R<1>, R<2>, R<3>, R<4> and R<5> are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.
|
| 申请公布号 |
EA006243(B1) |
申请公布日期 |
2005.10.27 |
| 申请号 |
EA20040000466 |
申请日期 |
2002.09.26 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
BLUMBERG, LAURA, COOK;BROWN, MATTHEW, FRANK;HAYWARD, MATTHEW, MERRILL;POSS, CHRISTOPHER, STANLEY;LUNDQUIST, GREGORY, DEAN, JR.;SHAVNYA, ANDREI |
| 分类号 |
C07D241/04;A61K31/495;A61K31/496;A61P9/10;A61P11/00;A61P29/00;A61P31/18;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D207/16;C07D213/63;C07D213/64;C07D213/74;C07D213/75;C07D213/76;C07D213/79;C07D213/80;C07D213/82;C07D239/34;C07D239/60;C07D257/04;C07D277/56;C07D295/185;C07D307/33;C07D307/68;C07D333/38;C07D401/06;C07D401/10;C07D401/12;C07D403/10;C07D405/10;C07D409/10;C07D417/10;(IPC1-7):C07D241/04 |
主分类号 |
C07D241/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
