CONSTRAINED ALKALOID IMMUNOGENS AND ANTIBODIES AND USES THEREOF

摘要

Immunogens useful in the production of anti-nicotine antibodies are provided. Anti-nicotine antibodies that immunoreact with the immunogens and nicotine and uses of the immunogens and antibodies in treating nicotine addiction are also provided. Also provided are methods for enhancing the immunogenicity of a hapten by introducing a modification to constrain its conformation.