发明名称 |
METHODS OF THERAPY AND DIAGNOSIS USING TARGETING OF CELLS THAT EXPRESS KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR-LIKE PROTEIN |
摘要 |
Certain cells, including types of cancer cells such as KIRHy1, are capable of expressing KIRHy1 mRNA. Targeting using KIRHy1 polypeptides, nucleic acids encoding for KIRHy1 polypeptides and anti-KIRHy1 antibodies provides a method of killing or inhibiting that growth of cancer cells that express the KIRHy1 protein. Methods of therapy and diagnosis of disorders associated with KIRHy1 protein-expressing cells, such as acute myelogenous leukemia (AML), are described. |
申请公布号 |
WO2005060375(A3) |
申请公布日期 |
2005.10.27 |
申请号 |
WO2004US11171 |
申请日期 |
2004.04.13 |
申请人 |
NUVELO, INC.;EMTAGE, PETER, C.R. |
发明人 |
EMTAGE, PETER, C.R. |
分类号 |
A61K38/00;A61K39/395;A61K47/48;A61K51/00;A61K51/10;C07H21/02;C07H21/04;C07K14/705;C07K16/28;C07K16/30;C07K16/46;C12Q1/68;G01N33/574;G01N33/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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