ONCOLYTIC HERPES SIMPLEX VIRUS ENCODING A HETEROLOGOUS NITROREDUCTASE
摘要
An herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding a nitroreductase (NTR) is disclosed. Disclosed herpes simplex viruses are indicated to be useful in the treatment of cancer which may involve gene directed enzyme prodrug therapy.
申请公布号
WO2005049845(A3)
申请公布日期
2005.10.27
申请号
WO2004GB04851
申请日期
2004.11.17
申请人
CRUSADE LABORATORIES LIMITED;BROWN, SUSANNE, MOIRA;DUNN, PAUL
