| 发明名称 |
INHIBITORS OF AKT ACTIVITY |
| 摘要 |
The present invention is directed to compounds which contain substituted pyridazines and pyrimidines moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of th e invention.
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| 申请公布号 |
CA2561311(A1) |
申请公布日期 |
2005.10.27 |
| 申请号 |
CA20052561311 |
申请日期 |
2005.04.05 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
HOFFMAN, JACOB M.;COSFORD, NICHOLAS D. P.;NAGASAWA, JOHNNY YASUO;CHUA, PETER C.;BILODEAU, MARK T. |
| 分类号 |
C07D403/00;A61K31/501;A61K31/506;C07D401/14;C07D403/10;C07D403/14;C07D417/14 |
主分类号 |
C07D403/00 |
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