摘要 |
<p num="1"><br/><br/><br/>Methods to detect, screen, and quantitate biological samples after <br/>administration of antibody conjugates, antibody-drug conjugates of Formula <br/>(I), antibodies, and fragments and metabolites thereof, by affinity <br/>separation, chromatography, and mass spectrometry are disclosed. Ab-(L-D)p (I) <br/>wherein Ab is an antibody; D is a drug moiety; L is a linker covalently <br/>attached to Ab, and covalently attached to D; and p is 1, 2, 3, 4, 5, 6, 7, or <br/>8.<br/> |