发明名称 |
NOVEL MEDICAL USES OF 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES HAVING CB1- ANTAGONISTIC ACTIVITY |
摘要 |
Abstract of the Disclosure The present invention relates to a novel medical use of 4,5-dihydro-1H-pyrazole compounds which are potent antagonists of the cannabis CB<SUB>1</SUB>-receptor. Said compounds are particularly suitable in the manufacture of medicaments for the treatment and/or prophylaxis of CB<SUB>1</SUB> receptor related diseases in juvenile patients and/or for the treatment and/or prophylaxis of drug induced obesity in juvenile as well as in adolescent patients. The compounds have the general formula (I) wherein the group Bb represents sulfonyl or carbonyl, and the substituents R, R<SUB>1</SUB>, R<SUB>2</SUB> and R<SUB>3</SUB>, and the group Aa are defined as shown in the description.
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申请公布号 |
US2005239859(A2) |
申请公布日期 |
2005.10.27 |
申请号 |
US20040929377 |
申请日期 |
2004.08.31 |
申请人 |
SOLVAY PHARMACEUTICALS GMBH |
发明人 |
ANTEL JOCHEN;KRAUSE GUNTER;LANGE JOSEPHUS H.;KRUSE CORNELIS (.G.;GREGORY PETER-COLIN;DEN BESTEN CATHALINE |
分类号 |
A61K31/415;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/415 |
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