摘要 |
The invention provides a human GPRC5C which is associated with the cardiovascular diseases, dermatological diseases, endocrinological diseases, metabolic diseases, cancer, inflammation, gastroenterological diseases, hematological diseases, muscle skeleton disorders, neurological diseases, urological diseases and respiratory diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, dermatological diseases, endocrinological diseases, metabolic diseases, cancer, inflammation, gastroenterological diseases, hematological diseases, muscle skeleton disorders, neurological diseases, urological diseases and respiratory diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of GPRC5C as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |