发明名称 SUBSTITUTED TETRACYCLINE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT TETRACYCLINE COMPOUND-RESPONSIVE STATES
摘要 The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
申请公布号 EA006170(B1) 申请公布日期 2005.10.27
申请号 EA20030000134 申请日期 2001.06.29
申请人 TRUSTEES OF TUFTS COLLEGE;PARATEK PHARMACEUTICALS, INC. 发明人 NELSON, MARK, L.;BOWSER, TODD;BHATIA, BEENA;VERMA, ATUL;VISKI, PETER;ISMAIL, MOHAMED;KOZA, DARRELL;MCINTYRE, LAURA;MESSERSMITH, DAVID;RENNIE, GLEN;WARCHOL, TAD;FRECHETTE, ROGER;HAWKINS, PAUL;SHEAHAN, PAUL;BANDARAGE, UPUL
分类号 A61K31/65;A61P31/00;A61P31/04;C07C;C07C237/26;C07C251/04;C07C251/24;C07C251/48;C07C271/22;C07C271/28;C07C271/58;C07C275/24;C07C275/42;C07C311/06;C07D207/22;C07D213/50;C07D213/56;C07D213/64;C07D239/36;C07D261/18;C07D277/30;C07D277/42;C07D295/096;C07D295/135;C07D295/155;C07D307/54;C07D307/68;C07D307/79;C07D317/60;C07D333/24;C07D333/28;C07D333/60;C07F9/24;(IPC1-7):C07C237/26 主分类号 A61K31/65
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