发明名称 N-(1-BENZYL-2-OXO-2-(1-PIPERAZINYL)ETHYL)-1-PIPERIDINCARBOXAMID-DERIVATIVES AND RELATED COMPOUNDS USE AS CGRP-ANTAGONISTS FOR TREATING A HEADACHE
摘要 The invention relates to carboxylic acids and esters of a general formula (I), wherein Ar, R, R1, X1, X3, X4, Y and Y1 have a definition given in a claim 1. Said invention also relates to tautomers, the enantiomers, mixtures and salts thereof, in particular to physiologically compatible salts containing organic or inorganic acids or bases, drugs containing said compounds using them as CGRT antagonists for treating a headache and to method for the production and use thereof for producing and cleaning antibodies and as labelled compounds for RIA and ELISA biological dosages and, finally as auxiliary diagnostics or analytics for neutrotransmitters.
申请公布号 KR20050102621(A) 申请公布日期 2005.10.26
申请号 KR20057013088 申请日期 2005.07.14
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 BAUER ECKHART;GERLACH KAI;HURNAUS RUDOLF;MUELLER STEPHAN GEORG;RUDOLF KLAUS;SCHINDLER MARCUS;STENKAMP DIRK
分类号 A61K31/4545;C07D249/08;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D405/14;C07D417/06;C07D417/14;(IPC1-7):C07D401/14;C07D417/12 主分类号 A61K31/4545
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