发明名称 |
NOVEL PROTEIN AND ITS GENE |
摘要 |
With the object of providing a novel protein expression of which is specifically elevated in abnormal cells or abnormal tissue, and also providing a diagnostic method and diagnostic kit for diseases involving elevated expression of a gene encoding that protein, along with a screening method and screening kit for substances for preventing and treating diseases involving elevated expression of a gene encoding that protein, (a) a protein comprising the amino acid sequence represented by Seq. ID No. 2 or (b) a protein comprising the amino acid sequence represented by Seq. ID No. 2 with one or more amino acids deleted replaced or added is provided as a novel protein expression of which is specifically elevated in abnormal cells or abnormal tissue, with a protein expression of which is specifically elevated in abnormal cells or abnormal tissue, the level of expression of a gene encoding that protein is taken as a marker for diagnosing a disease and a reduction effect on the level of expression of a gene encoding that protein is taken as a marker for screening preventative and therapeutic substances for a disease. <IMAGE>
|
申请公布号 |
EP1589101(A1) |
申请公布日期 |
2005.10.26 |
申请号 |
EP20030768371 |
申请日期 |
2003.12.26 |
申请人 |
CHUGAI PHARMACEUTICAL CO., LTD.;TOUDAI TLO, LTD. |
发明人 |
ABURATANI, HIROYUKI;ITO, HIROTAKA;ISHIKAWA, SHUNPEI;FUKUMOTO, SHINICHI |
分类号 |
G01N33/574;C07K14/705;(IPC1-7):C12N15/09;G01N33/53 |
主分类号 |
G01N33/574 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|