| 发明名称 |
PREPARATION OF 1-BUTYL-4-PIPERIDINYLMETHYLAMINE |
| 摘要 |
A process for the preparation of 1-butyl-4-piperidinylmethylamine, which process comprises: i) the reaction of isonipecotamide and 1-bromobutane to give the N-butyl derivative of isonipecotamide; followed by ii) reduction with LiAlH4, characterised in that the reactions i) and ii) are carried out in toluene as solvent.
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| 申请公布号 |
CA2266468(C) |
申请公布日期 |
2005.10.25 |
| 申请号 |
CA19972266468 |
申请日期 |
1997.09.09 |
| 申请人 |
SMITHKLINE BEECHAM P.L.C. |
发明人 |
GUEST, DAVID WILLIAM;SMITH, GILLIAN ELIZABETH;FEDOULOFF, MICHAEL |
| 分类号 |
A61K31/5365;A61P1/00;A61P1/04;A61P43/00;C07D211/26;C07D498/04;(IPC1-7):C07D498/04 |
主分类号 |
A61K31/5365 |
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