| 摘要 |
A heteroduplex tracking assay (HTA), a hybridization based method of determining the genetic relationship between two or more viral genomes, for genotyping HCV is disclosed. The HTA for genotyping HCV was developed using single stranded probes derived from the carboxyl terminus of core and part of the E1 for HCV subtypes (1a, 1b, 2a, 2 b, and 3a). HTA is more accurate than RFLP for sub-typing HCV and has potential for identifying new variants and is useful for epidemiological studies.
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