发明名称 |
MONOCLONAL ANTIBODIES THAT BIND OR NEUTRALIZE DENGUE VIRUS |
摘要 |
The present invention relates to monoclonal antibodies that bind or neutralize dengue type 1, 2, 3, and/or 4 virus. The invention provides such antibodies, fragments of such antibodies retaining dengue virus-binding ability, fully human or humanized antibodies retaining dengue virus-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention. |
申请公布号 |
WO2005056600(A3) |
申请公布日期 |
2005.10.20 |
申请号 |
WO2004US40674 |
申请日期 |
2004.12.03 |
申请人 |
REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS;LAI, CHING-JUH;PURCELL, ROBERT, H. |
发明人 |
LAI, CHING-JUH;PURCELL, ROBERT, H. |
分类号 |
C07K16/10 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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