Novel CrtW carotenoid ketolase are provided that are useful for the production of ketocarotenoids. The ketolases genes of the present invention exhibit low homology in comparison to other CrtW ketolases previously reported. Expression of the carotenoid ketolases in heterologous hosts enabled production of canthaxanthin and astaxanthin. Coexpression experiments using divergent crtW genes resulted in increased production of the desired ketocarotenoids
申请公布号
WO2005062867(A3)
申请公布日期
2005.10.20
申请号
WO2004US43008
申请日期
2004.12.17
申请人
E.I. DUPONT DE NEMOURS AND COMPANY;CHENG, QIONG;TAO, LUAN;YAO, HENRY