METHOD AND SYSTEM FOR DUAL DOMAIN DISCRIMINATION OF VULNERABLE PLAQUE

摘要

A method for optically analyzing blood vessel walls comprises receiving optical signals from the vessel walls and resolving a spectrum of optical signals in wavelength to generate spectral data. The spectral data are then transformed into the frequency domain. In the preferred embodiment, this transformation is achieved by applying wavelet decomposition. In other embodiments other transform techniques such as Fourier analysis are applied. The spectral data in the frequency domain are then used to analyze the vessel walls. In the typical embodiment, the spectral data are used to analyze a disease state of blood vessels walls such as the presence of atherosclerotic plaques, and their state. Dual domain method enables the spectral signals from blood vessels to be analyzed simultaneously according to frequency and wavelength (time). Dual-Domain Regression Analysis (DRDA) and Dual-Domain Discrimination Analysis (DDDA) in combination with wavelet transform (WT) enable the modeling of signals simultaneously in both domains.