SYNERGISTIC ATTENUTATION OF VESICULAR STOMATITIS VIRUS, VECTORS THEREOF AND IMMUNOGENIC COMPOSITIONS THEREOF
摘要
<p>The present invention broadly relates to the synergistic attenuation of vesicular stornatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicitnof VSV vectors in mammals and imrPWnogenic compositions thereof.</p>
申请公布号
WO2005098009(A2)
申请公布日期
2005.10.20
申请号
WO2005US11499
申请日期
2005.04.05
申请人
WYETH;CLARKE, DAVID, KIRKWOOD;HENDRY, ROGER, MICHAEL;UDEM, STEPHEN, A.;PARKS, CHRISTOPHER, LEE
发明人
CLARKE, DAVID, KIRKWOOD;HENDRY, ROGER, MICHAEL;UDEM, STEPHEN, A.;PARKS, CHRISTOPHER, LEE