发明名称 |
Methods and compositions for inhibiting c-met dimerization and activation |
摘要 |
The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.
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申请公布号 |
US2005233960(A1) |
申请公布日期 |
2005.10.20 |
申请号 |
US20040010173 |
申请日期 |
2004.12.10 |
申请人 |
GENENTECH, INC. |
发明人 |
KONG-BELTRAN MONICA;WICKRAMASINGHE DINELI M. |
分类号 |
A61K38/00;A61K38/03;A61K38/08;A61K38/17;A61K38/18;C07K14/475;C07K16/18;C07K16/22;C07K16/32;G01N33/68;(IPC1-7):A61K38/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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