METHOD FOR PREPARING MODIFIED COLLAGEN OUTSIDE A HOST CELL
摘要
<p>The present invention relates to a method for preparing a modified folded protein, comprising modifying unfolded a-chains comprising a collagenous amino acid sequence and thereafter folding at least part of the modified a-chains into a quaternary protein structure, in particular a helical protein structure. The invention allows for an attractive alternative for making recombinant proteins, such as recombinant collagens and the like, which may be used in a variety of biomedical and other applications.</p>
申请公布号
WO2005097829(A1)
申请公布日期
2005.10.20
申请号
WO2005NL00264
申请日期
2005.04.07
申请人
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO;BANK, RUDOLF, ANTONIUS;ZUURMOND, ANNE-MARIE;JORE, JOHANNES, PETRUS, MARIA
发明人
BANK, RUDOLF, ANTONIUS;ZUURMOND, ANNE-MARIE;JORE, JOHANNES, PETRUS, MARIA