SYSTEM AND METHOD FOR REAL-TIME DIAGNOSIS, TREATMENT, AND THERAPEUTIC DRUG MONITORING
摘要
Systems and methods for diagnosing and/or treating diseases as well as monitoring disease treatment. For diagnosis, the present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker; and a means for detecting a specific chemical entity. In certain embodiments, nanoparticle-based assemblies include a payload for simultaneous diagnosis and treatment of disease. In further embodiments, a therapeutic drug and therapeutic drug marker are administered to a patient to monitor disease treatment. Bodily fluid samples are analyzed using sensor technology to detect the presence of surrogate and/or therapeutic drug markers to provide an efficient and accurate means for diagnosing a disease and/or monitoring disease treatment.
申请公布号
WO2005098429(A2)
申请公布日期
2005.10.20
申请号
WO2005US06355
申请日期
2005.02.28
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;MELKER, RICHARD, J.;SACKELLARES, JAMES, CHRIS;GOLD, MARK, S.;DENNIS, DONN, MICHAEL
发明人
MELKER, RICHARD, J.;SACKELLARES, JAMES, CHRIS;GOLD, MARK, S.;DENNIS, DONN, MICHAEL