发明名称 ИНГИБИТОРЫ ЦИСТЕИНПРОТЕАЗЫ 2-ЦИАНО-4-АМИНОПИРИМИДИНОВОГО СТРОЕНИЯ С ИНГИБИРУЮЩИМ ДЕЙСТВИЕМ НА КАТЕПСИН К ДЛЯ ЛЕЧЕНИЯ ВОСПАЛИТЕЛЬНЫХ И ДРУГИХ ЗАБОЛЕВАНИЙ
摘要 The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof (I), wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g., various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
申请公布号 RU2004109812(A) 申请公布日期 2005.10.20
申请号 RU20040109812 申请日期 2002.08.29
申请人 НОВАРТИС АГ (CH) 发明人 АЛЬТМАН Эва (CH);ХАЯКАВА Кенджи (JP);ИВАСАКИ Генджи (JP)
分类号 A61K31/505;A61P1/02;A61P9/10;A61P11/00;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P21/04;A61P29/00;A61P33/00;A61P33/06;A61P33/12;A61P35/00;A61P37/02;A61P43/00;C07D239/42;C07D401/12;C07D403/12 主分类号 A61K31/505
代理机构 代理人
主权项
地址