发明名称 |
Medicament for the prevention and/or the treatment of ischemic heart and peripheral vascular diseases, tumour development and for wound healing |
摘要 |
<p>The present invention is related to a compound or a pharmaceutical composition thereof for the use of a medicament in the modulation of angiogenesis through the tackling of the intracellular free cholesterol-caveolin1-eNOS-NO pathway. The present invention also provides a method of study, testing, screening and manufacturing of new compounds or compositions which influences the angiogenesis via said pathway with the aim of identifying a compound or composition having possible therapeutic or prophylactic properties upon ischemic heart and peripheral vascular diseases including cerebral diseases, tumour development and wound healing.</p> |
申请公布号 |
EP1586644(A2) |
申请公布日期 |
2005.10.19 |
申请号 |
EP20050012435 |
申请日期 |
2000.08.09 |
申请人 |
UNIVERSITE CATHOLIQUE DE LOUVAIN |
发明人 |
BALLIGAND, JEAN-LUC;FERON, OLIVIER |
分类号 |
A61K31/00;A61K31/40;A61K31/70;A61K38/00;A61K38/08;A61K38/17;A61K38/44;A61K48/00;A61P9/00;A61P35/00;C07K14/705;C12N15/12;G01N33/50;G01N33/68;(IPC1-7):C12N15/12 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|