发明名称 |
Fusion proteins with parts of immunoglobulins, their production and use |
摘要 |
<p>A soluble fusion protein (I) comprising a human protein (II), or part of it, that is not of the immunoglobulin (Ig) family and different parts (III) of Ig molecules of any subclass, is new. An independent claim is also included for a method for preparing (I) by introducing a DNA that encodes it into a mammalian cell expression system, expressing (I), and purification by affinity chromatography through the Ig component. ACTIVITY : Hemostatic; Immunosuppressive; Antiallergic; Antianemic; Anticoagulant; Thrombolytic. No details of tests for these activities are given. MECHANISM OF ACTION : Protein substitution or inhibition.</p> |
申请公布号 |
EP1586635(A1) |
申请公布日期 |
2005.10.19 |
申请号 |
EP20050011561 |
申请日期 |
1991.06.22 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH;THE GENERAL HOSPITAL CORPORATION |
发明人 |
LAUFFER, LEANDER, DR.;OQUENDO, PATRICIA, DR.;ZETTLMEISSL, GERD, DR.;SEED, BRIAN, DR. |
分类号 |
C07K14/195;A61K38/00;A61K39/395;A61P7/04;A61P9/00;A61P13/12;A61P37/02;A61P37/08;C07K1/22;C07K14/005;C07K14/47;C07K14/505;C07K14/52;C07K14/53;C07K14/535;C07K14/54;C07K14/545;C07K14/55;C07K14/705;C07K14/71;C07K14/715;C07K14/745;C07K16/00;C07K19/00;C12N5/10;C12N9/64;C12N15/09;C12N15/62;C12P21/02;C12R1/91;G01N33/15;G01N33/50;G01N33/68;(IPC1-7):C12N9/64 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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