摘要 |
<p>An apparatus for sonoporation comprising an ultrasound source and positioning means such as an optical trap, magnetic field or electrical field for positioning one or more microbubbles at a predetermined distance (Z axis) from a surface. In use, the ultrasound source produces an ultrasound signal capable of rupturing the one or more microbubbles when the one or more microbubbles is held at said predetermined position in order to mark, etch or puncture the surface.</p> |