发明名称 |
Nitrogenous heterocylic compounds |
摘要 |
The present invention relates to nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention is also related to a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases. In a particular aspect the present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which inhibit phosphorylation of a PDGF receptor to hinder abnormal cell growth and cell wandering, and a method for preventing or treating cell-proliferative diseases such as arteriosclerosis, vascular reobstruction, cancer and glomerulosclerosis.
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申请公布号 |
US6956039(B2) |
申请公布日期 |
2005.10.18 |
申请号 |
US20040344737 |
申请日期 |
2004.03.18 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
PANDEY ANJALI;SCARBOROUGH ROBERT M.;MATSUNO KENJI;ICHIMURA MICHIO;NOMOTO YUJI;IDE SHINICHI;TSUKUDA EIJI;SASAKI JUNKO;ODA SHOJI |
分类号 |
A61P35/00;C07D239/94;C07D401/12;C07D403/12;(IPC1-7):C07D487/00 |
主分类号 |
A61P35/00 |
代理机构 |
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地址 |
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