| 发明名称 |
Substituted phenylacetamides and their use as glucokinase activators. |
| 摘要 |
2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes. |
| 申请公布号 |
ZA200407986(B) |
申请公布日期 |
2005.10.18 |
| 申请号 |
ZA20040007986 |
申请日期 |
2004.10.04 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
WENDY LEA CORBETT;NANCY-ELLEN HAYNES;PAIGE ERIN MAHANEY;RAMAKANTH SARABU;JOSEPH SAMUEL GRIMSBY;ROBERT FRANCIS KESTER;RACHA FRANCIS;KUMAR JAGDISH;KA WANG |
| 分类号 |
C07D277/20;A61K31/17;A61K31/341;A61K31/351;A61K31/426;A61K31/427;A61K31/44;A61K31/4433;A61K31/4965;A61K31/497;A61P3/10;C07C273/18;C07C275/50;C07D213/75;C07D241/20;C07D277/44;C07D277/46;C07D307/16;C07D309/04;C07D309/06;C07D405/12;C07D409/12;C07D417/12 |
主分类号 |
C07D277/20 |
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