CARBOXY SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS

摘要

The present invention relates to novel carboxy substituted acyclic carboxami de derivatives of formula (1), and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin recept or antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.